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Tick-Borne Diseases - Knowledge of High School Students
Vlček, Karel ; Pavlasová, Lenka (advisor) ; Ehler, Edvard (referee)
Tick-borne diseases are caused by a group of pathogenic microorganisms which are transmitted between animal and human population by vector which is most frequently tick. Evaluation of danger and perils of these diseases is important due to prevention and monitoring of current situation development. The most common tick-borne diseases in the Czech Republic are borreliosis, tick-borne encephalitis and ehrlichiosis. Rarely can we encounter bartonellosis, babesiosis, rickettsiosis and tularemia. All these diseases can have serious consequences and in critical cases they can result in death of the infected person. One of the basic and the most important of preventive measures which lower the risk of the infection by any tick-borne disease is prevention of tick encounter and eventually vaccination. Due to continual global warming we can expect that in near future ticks will spread even to locations which have been so far not suitable for their development. We can expect that we will even more frequently encounter tick-borne diseases - including diseases which were formerly not found in our territory or were very rare. As a part of health education it will be needed more to get known basic information of tick-borne diseases and their prevention. Different educational centres are an ideal place for...
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Intracellular life of pathogenic bacterium Francisella tularensis in the host.
Rädisch, Robert ; Konopásek, Ivo (advisor) ; Vopálenská, Irena (referee)
Francisella tularensis is a facultative intracellular pathogenic bacterium, which causes disease named tularemia. For the entrance to the host cells Francisella uses host's cell mechanisms by which it is incorporated into cell phagosome. Subsequently, it escapes from phagosome to cytosole where bacterial growth takes place. Some of bacteria are cleared from cytosol by autophagy, from another ones dsDNA is released. This DNA is recognized by cytosolic receptors, which form inflammasome complex. Inflammasome sets off pathway leading to the death of infected cell. Since the penetration to the cell Francisella modulates cell signallization in its own benefit to ensure enough time and nutrients for its growth. Francisella do not act only in the infected cells, where it reduces recognition of itself and clearance from cytosol, but it also induces secretion of factors, which moderate activation of adaptive immunity of the host. Key words: Francisella, tularemia, fagosome, inflammasome, autophagy, adaptive immunity
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Tick-Borne Diseases - Knowledge of High School Students
Vlček, Karel ; Pavlasová, Lenka (advisor) ; Ehler, Edvard (referee)
Tick-borne diseases are caused by a group of pathogenic microorganisms which are transmitted between animal and human population by vector which is most frequently tick. Evaluation of danger and perils of these diseases is important due to prevention and monitoring of current situation development. The most common tick-borne diseases in the Czech Republic are borreliosis, tick-borne encephalitis and ehrlichiosis. Rarely can we encounter bartonellosis, babesiosis, rickettsiosis and tularemia. All these diseases can have serious consequences and in critical cases they can result in death of the infected person. One of the basic and the most important of preventive measures which lower the risk of the infection by any tick-borne disease is prevention of tick encounter and eventually vaccination. Due to continual global warming we can expect that in near future ticks will spread even to locations which have been so far not suitable for their development. We can expect that we will even more frequently encounter tick-borne diseases - including diseases which were formerly not found in our territory or were very rare. As a part of health education it will be needed more to get known basic information of tick-borne diseases and their prevention. Different educational centres are an ideal place for...
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Infectious diseases related to floods; protection of population and of Integrated Rescue System bodies at performing clean-up works in affected regions
BRAVENEC, Roman
In the recent years, floods have been an increasingly common natural phenomenon in the territory of the Czech Republic. I have chosen the bachelor thesis about the topic ?Infection diseases in connection with floods, protection of inhabitants and IRS forces when realizing clean-up operations in disaster areas? because I have been employed with the village of Loučovice in the position of the secretary. Due to its position on the flow of the Vltava River and below the water dam LIPNO 1, the village of Loučovice is threatened with both natural and special floods; therefore, timely awareness of citizens in case of possible threat is a basic prerequisite for the realization of effective measures for the protection of lives, health and property but also for possible elimination of effects of the flood. The paper summarizes possible causes of natural and special floods, which, in addition to considerable property damages, bring health risks too. As for the findings from the areas damaged by floods, I have identified the mostly occurring infection diseases after the flood goes off. In addition to the affected inhabitants, members of the intervention forces of the Integrated Rescue System and volunteers, who participate in rescue and clean-up operations, are also exposed to the infection diseases. Furthermore, I specify the evaluation of the statistical data identified in the system EPIDAT, which is used for monitoring of the epidemiological situation in the Czech Republic. The purpose of my paper is to gather collective information for the Flood Commission at the village of Loučovice. It concerns an overview of IRS forces and roles of the territorial self-governing units and their activity at the time of an extraordinary event. The result is an up-dated list of telephone contacts, so-called crisis card, recommendations for protection of property against the impact of the flood wave, possibilities of protection of water sources and the way of emergency supplies of drinking water, which are related to the threat of contagion with infection disease.
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